Advanced Courses – FEBS https://www.febs.org Just another WordPress site Wed, 05 Mar 2025 13:41:08 +0000 en-GB hourly 1 https://wordpress.org/?v=6.7.2 The evolving role of mitochondria in metabolism https://www.febs.org/event/the-evolving-role-of-mitochondria-in-metabolism/ Fri, 13 Dec 2024 10:19:01 +0000 https://www.febs.org/?post_type=events&p=9624 Continued]]>

Mitochondria are vital organelles that produce energy and regulate cellular metabolism. While primarily known for generating ATP through oxidative phosphorylation, recent research highlights their broader influence on biological processes. Beyond energy production, mitochondria shape organismal fitness, adaptation, and life-history strategies by balancing metabolic efficiency, reactive oxygen species (ROS) production, and heat generation. These mechanisms affect performance, ecological interactions, and evolution. Now seen as dynamic regulators rather than mere energy producers, mitochondria integrate multiple metabolic pathways to influence physiology from the cellular to the organismal level. This expanded understanding has advanced ecology and evolutionary biology, offering insights into how organisms adapt to energetic demands and environmental pressures. This ‘Joint FEBS/EMBO Lecture Course’ aims to bring together experts from evolutionary biology, molecular biology, and biochemistry to delve deeper into mitochondrial biology. This interdisciplinary platform will expose students and researchers to diverse perspectives, fostering discussions that inspire innovative research. By combining expertise across fields, the series will highlight mitochondria’s multifaceted roles and their profound impact on metabolism, physiology, and evolution. (Thumbnail photo credit: Alexandra Kukat)

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]]> 2nd FEBS Redox Medicine Workshop: Connecting the exposome with redox regulation in health and disease https://www.febs.org/event/2nd-febs-redox-medicine-workshop-connecting-the-exposome-with-redox-regulation-in-health-and-disease/ Fri, 13 Dec 2024 09:41:03 +0000 https://www.febs.org/?post_type=events&p=9616 Continued]]> The 2nd FEBS Workshop on Redox Medicine will focus on “Connecting the exposome with redox regulation in health and disease”, reflecting the importance of the emerging knowledge on the multifaceted interaction with the external environment, collectively termed the exposome. The workshop will explore the dynamic redox regulation of signaling pathways observed for physiological concentrations of biological oxidants (oxidative eustress) and the dysregulation of redox homeodynamics (oxidative distress), commonly observed in several pathophysiological conditions, highlighting the importance of redox biology in medicine, both from the physiological but also the pathological perspective. The main goal is to promote an environment where young researchers can interact with prominent senior researchers. Join us for a workshop that includes lectures by invited speakers and short presentations by participants selected from submitted abstracts.

The event website is under preparation.

]]> Molecular and cellular pathways of aging in hematopoiesis https://www.febs.org/event/molecular-and-cellular-pathways-of-aging-in-hematopoiesis-2/ Tue, 03 Dec 2024 15:08:22 +0000 https://www.febs.org/?post_type=events&p=9555 Continued]]> Ageing is associated with an increased risk of developing various blood disorders, either malignant, e.g. myelodysplastic syndromes, or non-malignant, e.g. anemias. However, the molecular and cellular pathways in hematopoietic aging and associated hematological disease remain poorly understood. To address gaps in our knowledge, our Workshop will bring together basic, translational and clinical scientists to discuss key regulators of hematopoietic stem cell ontogeny, cell fate specification and self-renewal upon aging and malignant transformation, highlighting state-of-the-art technologies such as imaging, single-cell sequencing and model systems. The FEBS Workshop is also supported by the JM Foundation and will take place in the beautiful setting of Sissi in Crete.

The event website is under development.

]]> Computational approaches to understanding and engineering enzyme catalysis https://www.febs.org/event/computational-approaches-to-understanding-and-engineering-enzyme-catalysis-2/ Mon, 18 Nov 2024 12:26:13 +0000 https://www.febs.org/?post_type=events&p=9376 Continued]]> This FEBS Combined Practical & Lecture Course is intended to bring together computational and experimental enzymologists who will give comprehensive lectures towards understanding and engineering enzyme catalysis and protein chemistry. Hands-on practical sessions will be focused on how to use state-of-the-art software and web servers to understand carefully chosen phenomena in this research field. Experimental researchers will give lectures on how these in silico approaches have successfully helped them with solving problems in their research related to understanding and engineering enzyme catalysis and protein function.

]]> Physical virology: across length scales https://www.febs.org/event/physical-virology-across-length-scales/ Fri, 08 Nov 2024 08:55:24 +0000 https://www.febs.org/?post_type=events&p=9357 Continued]]> Our preparedness against viral diseases and our ability to exploit viral structures and their mechanisms of action to advance technology both require transdisciplinary collaborations. The EMBO|FEBS Lecture Course “Physical Virology: across length scales” aims at gathering researchers from various scientific disciplines with a common interest in viruses and at inspiring a new generation of transdisciplinary virus-oriented scientists. The program will address fundamental aspects of infection across the length scales from a transdisciplinary vantage point. It will further highlight promising methodological developments for the field of physical virology before addressing applied aspects of virology (virus-inspired materials, therapeutics and diagnostics).

]]> Immunology, metabolism and ageing https://www.febs.org/event/immunology-metabolism-and-ageing/ Thu, 31 Oct 2024 10:57:27 +0000 https://www.febs.org/?post_type=events&p=9249 Continued]]> An in-depth understanding of the molecular mechanisms underlying the ageing process, the immune response in old age, and the role of both processes on the pathophysiology of age-related diseases is crucial for defining strategies and treatments to improve health in old age and thereby developing sustainable future societies. This FEBS Workshop will combine the topics of immunology, metabolism and ageing in a unique way to highlight the intricate interplay of immunological and metabolic functions in the context of ageing and cellular senescence. Our meeting will bring together internationally renowned experts in immunological, metabolic and ageing research and provide ample opportunities for scientific exchange and informal interactions. We aim to connect experienced scientists and young researchers to foster potential collaborations and, hopefully, future careers to contribute to solutions for the biomedical challenges caused by the ongoing demographic shift. The deadline for abstract submission and application is 30 June 2025.

]]> Biological surfaces and interfaces: biointerfaces at lipids, proteins and polymers https://www.febs.org/event/biological-surfaces-and-interfaces-biointerfaces-at-lipids-proteins-and-polymers/ Thu, 31 Oct 2024 07:41:48 +0000 https://www.febs.org/?post_type=events&p=9242 Continued]]> Supported by the European Science Foundation (ESF), EMBO, and FEBS, biological surfaces and interfaces meetings running between 2003 and 2022 (8 editions) have been the forum for exchange of ideas between scientists active in this area, and a uniquely supportive environment for the training of young interdisciplinary scientists. With the 2025 meeting, we will focus on a new aspect of research into biointerfaces: the understanding of the complex interactions at the biointerfaces at the molecular level, by introducing cutting-edge techniques such as machine learning, big data approach such as hyperspectral microscopy, friction force microscopy, CRISPR-based genetic engineering tools, small-angle X-ray scattering, neutron reflectometry. The course will provide insights in dynamic processes at the interface between lipids, proteins (including enzymes and peptides) and bio- and nanomaterials, also shedding light on how specific electrolytes modulate the interactions among them. Additionally, the design of interfaces which provide dynamic and controlled spatio-temporal stimuli, as well as the drug design, by controlling the behaviour of protein–drug, lipid–drug, or also protein/enzyme–nanoparticle interfaces, will be presented. The workshop aims at understanding a multidisciplinary area – biological interfaces – from a more biophysical point of view, which is a unique perspective.

]]> Time-resolved spectroscopy meets time-resolved crystallography: the future of dynamic photobiology https://www.febs.org/event/time-resolved-spectroscopy-meets-time-resolved-crystallography-the-future-of-dynamic-photobiology/ Thu, 31 Oct 2024 07:25:57 +0000 https://www.febs.org/?post_type=events&p=9239 Continued]]> This workshop aims to bridge the two different disciplines of biophysics and dynamic structural biology, covering time-resolved spectroscopic (optical and vibrational spectroscopy) and X-ray techniques (crystallography and scattering at synchrotrons and XFELs). The synergy of the experimental techniques will be complemented by computational approaches. Particular attention will be given to fostering collaborations between experts from these different areas and to the training of young researchers. To that end the lectures will have a strong educational element including training sessions with hands-on experience in the analysis of time-resolved spectroscopic and crystallographic data.

The following topics will be covered: time-resolved spectroscopy (infrared, Raman, circular dichroism, fluorescence), time-resolved serial crystallography at synchrotrons and XFELs, time-resolved cryo EM, fast-mixing techniques, sensory photoreceptors of optogenetic interest, rhodopsins, heme proteins, flavoproteins, cryptochromes, LOV domains, BLUF domains, UV-damage, computational biology (MD simulations, DFT, QM/MM), photophysics, membrane proteins, photosynthetic systems and software development for serial crystallography.

]]> European workshop on bacterial protein toxins https://www.febs.org/event/european-workshop-on-bacterial-protein-toxins/ Tue, 29 Oct 2024 16:36:18 +0000 https://www.febs.org/?post_type=events&p=9201 Continued]]> Hosted in the picturesque setting of Arantzazu, Spain, this FEBS Workshop – the  22nd European Workshop on Bacterial Protein Toxins (ETOX 2025) – gathers experts to explore critical developments in bacterial toxicology. Key topics will include the mechanisms of bacterial secretion systems (T3SS, T4SS, T5SS, T6SS, and T7SS), toxin–host interactions and immune response, and toxin structure and function. Esteemed speakers from around the globe will guide these sessions, joined by emerging scientists selected from abstracts.

The organizers, alongside an international advisory board, invite applications from researchers worldwide, with a submission deadline of 31 January 2025. Join us for an inspiring journey into the molecular world of bacterial protein toxins and a chance to foster collaborative advancements in this vital field.

]]> Expanding frontiers in aminoacyl-tRNA synthetase research https://www.febs.org/event/expanding-frontiers-in-aminoacyl-trna-synthetase-research/ Tue, 29 Oct 2024 16:12:48 +0000 https://www.febs.org/?post_type=events&p=9197 Continued]]> Aminoacyl-tRNA synthetases (AARS) are valuable models for studying the evolution of enzyme selectivity and the genetic code. Their key role in protein synthesis places them as central figures in the rapidly developing fields of synthetic biology, drug design, and human biomedicine. The FEBS Special Meeting ‘Expanding frontiers in aminoacyl-tRNA synthetase research’ will present a unique opportunity to discuss various aspects of the AARS research, including mechanisms, evolution, cellular function, and diseases, jointly with AARS-related topics such as protein quality control and peptide synthesis and evolution. A session promoting interactions between basic scientists, physicians, the pharmaceutical industry and patients with AARS-related diseases will be organized to support cross-field interactions in Europe and worldwide.

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